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KMID : 0613320030090010045
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Journal of the Korean Bone and Joint Tumor Soceity
2003 Volume.9 No. 1 p.45 ~ p.51
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Quantitative Analysis of Thallium-201 Scintigraphy in Bone Tumor
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Shin Duk-Seop
Cho Ihn-Ho
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Abstract
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Purpose : This study was designed to know the ability of thallium-201 scintigraphy to discriminate malignant bone tumor from benign by analysing the quantitative thallium uptake ratio.
Materials and Methods : We took thallium-201 scintigraphy prospectively with other imaging studies in 82 bone tumor suspecting patients. The results of scintigraphy were read qualitatively and calculated quantitatively, and retention indexes were estimated. For the statistical analysis the patients were divided as four group; high grade malignant bone tumor, benign bone tumor, giant cell tumor and low grade malignant bone tumor.
Results : The mean thallium uptake ratio was 4.14 in early phase and 2.26 in delayed pahse in high grade malignant bone tumor group, 1.16 and 1.09 in benign boen tumor, 3.15 and 1.94 in giant cell tumor, and 1.41 and 1.31 in low grade malignant bone tumor.
Retention indexes were 0.62, 0.97, 0.66, 0.93 in same order. The thallium uptake ratio and retention indexes were statistically correlated in high grade malignant bone tumor and benign bone tumor group(p<0.001).
Conclusion : Thallium-201 scintigraphy proved as useful imaging study to discriminate malignant bone tumor from benign, but had exception in giant cell tumor and low grade malignant bone tumors.
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KEYWORD
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Bone tumor, Thallium-201 scintigraphy, Quantitative analysis
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